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Case Report
 
Cytological diagnosis of metastatic deposits of alveolar rhabdomyosarcoma in ascitic fluid: A rare case report
Meera P.P.1, Bhulaxmi P.2, Nikhil S. Ghadyalpatil3
1MD, Consultant Pathologist, Department of Pathology, Yashoda Hospital, Hyderabad, Telangana, India.
2MD, HOD and Consultant Pathologist, Department of Pathology, Yashoda Hospital, Hyderabad, Telangana, India.
3MD, DM, Consultant Medical Oncologist, Department of medical oncology, Yashoda Hospital, Hyderabad, Telangana India.

Article ID: 100013OCYMP2016
doi:10.5348/OCY-2016-13-CR-3

Address correspondence to:
Meera P.P.
Consultant Pathologist, Yashoda hospital
Somajiguda, Hyderabad
Telangana
India, 500082

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How to cite this article
Meera PP, Bhulaxmi P, Ghadyalpatil NS. Cytological diagnosis of metastatic deposits of alveolar rhabdomyosarcoma in ascitic fluid: A rare case report. Oncocytology 2016;6:8–11.


Abstract
Introduction: Rhabdomyosarcoma is an uncommon tumor seen in young adolescents and adults that metastasizes to the peritoneum.
Case Report: Here we report a case of 18-year-old female who had alveolar rhabdomyosarcoma of nose and was treated with chemoradiotherapy. After one year, she presented with ascites. Ascitic fluid cytology revealed deposits of rhabdomyosarcoma. Immunohistochemistry done to support the diagnosis. This case report highlights the cytological features of rhabdomyosarcoma cells, which were large pleomorphic with high nuclear cytoplasmic ratio, coarse chromatin and scant cytoplasm. A small population of cells was almost the size of mesothelial cells, which could be mistaken for a reactive mesothelial cells.
Conclusion: Awareness of rare metastases of rhabdomyosarcoma in peritoneum and recognition of the cytological features of these malignant cells supported by specific immunostains helps in the diagnosis.

Keywords: Cytological features, Immunohistochemistry, Myogenin, Rhabdomyosarcoma


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Author Contributions
Meera P.P. – Substantial contributions to conception and design, Acquisition of data, Analysis and interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Bhulaxmi P. – Substantial contributions to conception and design, Analysis and interpretation of data, Drafting the article, Final approval of the version to be published
Nikhil Ghadyal Patil – Substantial contributions to conception and design, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2016 Meera P.P. et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.